5. Sephiroth (Final Fantasy VII)
As if murdering the world’s favourite flower girl wasn’t enough, this psycho has some weird obsession with his mother. Want more? What about randomly burning down a village to show classic insanity?
4. Sander Cohen (Bioshock)
"Cohen's an artist, says some. He's a Section Eight, says I. I've seen all kinds of cutthroats, freaks, and hard cases in my life, but Cohen, he's a real lunatic, a dyed-in-the-wool psychopath..." - Atlas
There comes a point where a commitment to artwork goes too far. When it turns out that your actors are a just murderers in bunny suits, or when your “masterpiece” is a bunch of pictures of dead bodies, perhaps you’ve lost your way. Still, Rapture was perhaps the perfect place for Sander Cohen.3. Psycho Mantis (Metal Gear Solid series)
I don’t think it gets worse when there’s a nutcase with mind powers. He joined FOXHOUND just for a chance to kill as many people as possible. However, the real mental problem with Mantis is he still hasn’t figured out it was actually DualShock that moved our controllers.
2. Cloud Strife (Final Fantasy VII)
Unlike his archrival Sephiroth (or anyone else on this list), Cloud is not responsible for killing numerous innocents. However, Cloud’s psychological state would probably be a more textbook case of mental illness; he developed dissociative identity disorder when he took up the personality and likeness of fallen comrade Zack.
1. Dr. Wily (Mega Man Series)
Gaming has more than a few madmen who, for some unknowable reason, have the urge to take over the world. This madness doesn’t extend further than Dr. Wily who has attempted to control the world not once, but ten times (probably more, actually)! Talk about obsessive-compulsive disorder.